منابع مشابه
Protamines. Isolation, characterization, structure and function.
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متن کاملProtamines: structural complexity, evolution and chromatin patterning.
Despite their relatively arginine-rich composition, protamines exhibit a high degree of structural variation. Indeed, the primary structure of these histone H1-related sperm nuclear basic proteins (SNBPs) is not random and is the depository of important phylogenetic information. This appears to be the result of their fast rate of evolution driven by positive selection. The way by which the prot...
متن کاملAllelic Expression of Drosophila Protamines during Spermatogenesis
In typical somatic cells, DNA is tightly organized by histones that are necessary for its proper packaging into the nucleus. In sexually-reproducing animals, the haploid product of male meiosis must be further condensed to fit within sperm heads, thus requiring an even greater degree of packaging. This is accomplished in most organisms by replacing histones with protamines, which allows DNA to ...
متن کاملProtamines and spermatogenesis in Drosophila and Homo sapiens
The production of mature and motile sperm is a detailed process that utilizes many molecular players to ensure the faithful execution of spermatogenesis. In most species that have been examined, spermatogenesis begins with a single cell that undergoes dramatic transformation, culminating with the hypercompaction of DNA into the sperm head by replacing histones with protamines. Precise execution...
متن کاملAllergic reaction to protamine: a late complication of elective vasectomy?
Nucleoprotamines are a normal component of human sperm cells. Antibodies against these protamines develop in 22 to 33 per cent of patients undergoing elective vasectomy. These antibodies, in turn, have been shown to cross-react with medicinal protamines, which are extracted commercially from the testes of salmon and certain other fish. This cross-reactivity against protamines raises the possibi...
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ژورنال
عنوان ژورنال: Progress in Biophysics and Biophysical Chemistry
سال: 1956
ISSN: 0096-4174
DOI: 10.1016/s0096-4174(18)30102-1